Stem cells in homeostasis and cancer of the gut

Abstract The intestinal epithelial lining is one of the most rapidly renewing cell populations in the body. As a result, the gut has been an attractive model to resolve key mechanisms in epithelial homeostasis. In particular the role of intestinal stem cells (ISCs) in the renewal process has been in...

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Bibliographic Details
Main Authors: Maartje van der Heijden, Louis Vermeulen
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Molecular Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12943-019-0962-x