Hantaan virus infection induces both Th1 and ThGranzyme B+ cell immune responses that associated with viral control and clinical outcome in humans.

Hantaviruses infection causing severe emerging diseases with high mortality rates in humans has become public health concern globally. The potential roles of CD4(+)T cells in viral control have been extensively studied. However, the contribution of CD4(+)T cells to the host response against Hantaan...

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Bibliographic Details
Main Authors: Ying Ma, Bin Yuan, Ran Zhuang, Yusi Zhang, Bei Liu, Chunmei Zhang, Yun Zhang, Haitao Yu, Jing Yi, Angang Yang, Boquan Jin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4383613?pdf=render