The modulation of TRPM7 currents by nafamostat mesilate depends directly upon extracellular concentrations of divalent cations

<p>Abstract</p> <p>Concentrations of extracellular divalent cations (Ca<sup>2+ </sup>and Mg<sup>2+</sup>) fall substantially during intensive synaptic transmission as well as during some pathophysiological conditions such as epilepsy and brain ischemia. Here...

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Bibliographic Details
Main Authors: Chen Xuanmao, Numata Tomohiro, Li Minghua, Mori Yasuo, Orser Beverley A, Jackson Michael F, Xiong Zhi-Gang, MacDonald John F
Format: Article
Language:English
Published: BMC 2010-12-01
Series:Molecular Brain
Online Access:http://www.molecularbrain.com/content/3/1/38