Metabolic, mitochondrial, renal and hepatic safety of enfuvirtide and raltegravir antiretroviral administration: Randomized crossover clinical trial in healthy volunteers.

Metabolic, mitochondrial, renal and hepatic safety of enfuvirtide and raltegravir antiretroviral administration: Randomized crossover clinical trial in healthy volunteers.

CONTEXT:Classical antiretroviral agents may acutely impact on metabolic, mitochondrial, renal and hepatic function in HIV-infected and uninfected persons. Fusion and integrase inhibitors are supposed to be safer, but have been scarcely investigated. To avoid any interference with HIV or other antire...

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Bibliographic Details
Main Authors: Sergio Barroso, Constanza Morén, Àlex González-Segura, Neus Riba, Joan A Arnaiz, Marcela Manriquez, Gemina Santana, José L Blanco, María Larousse, Montse Loncà, Elisa de Lazzari, Jaume Llopis, Josep Mallolas, Oscar Miró, Xavier Carné, Jose M Gatell, Glòria Garrabou, Esteban Martínez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0216712

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https://doi.org/10.1371/journal.pone.0216712

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