Common and Unique Transcription Signatures of YAP and TAZ in Gastric Cancer Cells

Common and Unique Transcription Signatures of YAP and TAZ in Gastric Cancer Cells

YAP and its paralog TAZ are the nuclear effectors of the Hippo tumour-suppressor pathway, and function as transcriptional co-activators to control gene expression in response to mechanical cues. To identify both common and unique transcriptional targets of YAP and TAZ in gastric cancer cells, we car...

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Bibliographic Details
Main Authors: Yaelim Lee, Megan Finch-Edmondson, Hamizah Cognart, Bowen Zhu, Haiwei Song, Low Boon Chuan, Marius Sudol
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
YAP (Yes-associated protein 1
also known as YAP1 or YAP65)
TAZ (transcriptional co-activator with PDZ-binding motif
also known as WWTR1)
gastric cancer
transcriptome
Online Access:https://www.mdpi.com/2072-6694/12/12/3667

Internet

https://www.mdpi.com/2072-6694/12/12/3667

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