Acute brain injuries trigger microglia as an additional source of the proteoglycan NG2

Acute brain injuries trigger microglia as an additional source of the proteoglycan NG2

Abstract NG2 is a type I transmembrane glycoprotein known as chondroitin sulfate proteoglycan 4 (CSPG4). In the healthy central nervous system, NG2 is exclusively expressed by oligodendrocyte progenitor cells and by vasculature pericytes. A large body of immunohistochemical studies showed that under...

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Bibliographic Details
Main Authors: Wenhui Huang, Xianshu Bai, Erika Meyer, Anja Scheller
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Acta Neuropathologica Communications
Subjects:
Microglia
Macrophage
OPCs
Pericytes
NG2
Gliosis
Online Access:http://link.springer.com/article/10.1186/s40478-020-01016-2

Internet

http://link.springer.com/article/10.1186/s40478-020-01016-2

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