Computational inference of cancer-specific vulnerabilities in clinical samples

Computational inference of cancer-specific vulnerabilities in clinical samples

Abstract Background Systematic in vitro loss-of-function screens provide valuable resources that can facilitate the discovery of drugs targeting cancer vulnerabilities. Results We develop a deep learning-based method to predict tumor-specific vulnerabilities in patient samples by leveraging a wealth...

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Bibliographic Details
Main Authors: Kiwon Jang, Min Ji Park, Jae Soon Park, Haeun Hwangbo, Min Kyung Sung, Sinae Kim, Jaeyun Jung, Jong Won Lee, Sei-Hyun Ahn, Suhwan Chang, Jung Kyoon Choi
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Genome Biology
Online Access:http://link.springer.com/article/10.1186/s13059-020-02077-1

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http://link.springer.com/article/10.1186/s13059-020-02077-1

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