A designer FG-Nup that reconstitutes the selective transport barrier of the nuclear pore complex

A designer FG-Nup that reconstitutes the selective transport barrier of the nuclear pore complex

Intrinsically disordered FG-Nups line the Nuclear Pore Complex (NPC) lumen and form a selective barrier where transport of most proteins is inhibited, whereas specific transporter proteins are able to pass. Here, the authors reconstitute the selective behaviour of the NPC by introducing a rationally...

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Bibliographic Details
Main Authors: Alessio Fragasso, Hendrik W. de Vries, John Andersson, Eli O. van der Sluis, Erik van der Giessen, Andreas Dahlin, Patrick R. Onck, Cees Dekker
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22293-y

Internet

https://doi.org/10.1038/s41467-021-22293-y

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