The role of C-terminal amidation in the mechanism of action of the antimicrobial peptide aurein 1.2

C-terminal amidation is a common feature of wild type membrane disrupting antimicrobial peptides (AMPs). Empirical evidence suggests that this modification increases antimicrobial efficacy. However, the actual role of C-terminal amidation in the molecular mechanism of action of AMPs is not fully und...

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Bibliographic Details
Main Authors: Shahmiri Mahdi, Mechler Adam
Format: Article
Language:English
Published: Sciendo 2020-01-01
Series:The EuroBiotech Journal
Subjects:
Online Access:https://doi.org/10.2478/ebtj-2020-0004