A genome-wide portrait of pervasive drug contaminants

Abstract Using a validated yeast chemogenomic platform, we characterized the genome-wide effects of several pharmaceutical contaminants, including three N-nitrosamines (NDMA, NDEA and NMBA), two related compounds (DMF and 4NQO) and several of their metabolites. A collection of 4800 non-essential hom...

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Bibliographic Details
Main Authors: Joseph Uche Ogbede, Guri Giaever, Corey Nislow
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91792-1