Interleukin-12p35 Knock Out Aggravates Doxorubicin-Induced Cardiac Injury and Dysfunction by Aggravating the Inflammatory Response, Oxidative Stress, Apoptosis and Autophagy in MiceResearch in context

Background: Recent evidence has demonstrated that interleukin 12p35 knockout (IL-12p35 KO) is involved in cardiac diseases by regulating the inflammatory response. The involvement of inflammatory cells has also been observed in doxorubicin (DOX)-induced cardiac injury. This study aimed to investigat...

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Bibliographic Details
Main Authors: Jing Ye, Ying Huang, Bin Que, Chao Chang, Wenjing Liu, Haiying Hu, Ling Liu, Ying Shi, Yuan Wang, Menglong Wang, Tao Zeng, Wang Zhen, Yao Xu, Lei Shi, Jianfang Liu, Huimin Jiang, Di Ye, Yingzhong Lin, Jun Wan, Qingwei Ji
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396418302111