The Taming of Nuclear Factor Erythroid-2-Related Factor-2 (Nrf2) Deglycation by Fructosamine-3-Kinase (FN3K)-Inhibitors-A Novel Strategy to Combat Cancers

The Taming of Nuclear Factor Erythroid-2-Related Factor-2 (Nrf2) Deglycation by Fructosamine-3-Kinase (FN3K)-Inhibitors-A Novel Strategy to Combat Cancers

Glycated stress is mediated by the advanced glycation end products (AGE) and the binding of AGEs to the receptors for advanced glycation end products (RAGEs) in cancer cells. RAGEs are involved in mediating tumorigenesis of multiple cancers through the modulation of several downstream signaling casc...

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Bibliographic Details
Main Authors: Narasimha M. Beeraka, Venugopal R. Bovilla, Shalini H. Doreswamy, Sujatha Puttalingaiah, Asha Srinivasan, SubbaRao V. Madhunapantula
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
glycation
deglycation
FN3K
Nrf2
RAGE
AGEs
Online Access:https://www.mdpi.com/2072-6694/13/2/281

Internet

https://www.mdpi.com/2072-6694/13/2/281

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