Neural network aided approximation and parameter inference of non-Markovian models of gene expression

Cells are complex systems that make decisions biologists struggle to understand. Here, the authors use neural networks to approximate the solution of mathematical models that capture the history and randomness of biochemical processes in order to understand the principles of transcription control.

Bibliographic Details
Main Authors: Qingchao Jiang, Xiaoming Fu, Shifu Yan, Runlai Li, Wenli Du, Zhixing Cao, Feng Qian, Ramon Grima
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22919-1