Rearrangements of the intermediate filament GFAP in primary human schwannoma cells

Rearrangements of the intermediate filament GFAP in primary human schwannoma cells

Loss of the tumor suppressor protein merlin causes a variety of benign tumors such as schwannomas, meningiomas, and gliomas in man. We previously reported primary human schwannoma cells to show enhanced integrin-dependent adhesion and a hyperactivation of the small RhoGTPase Rac1. Here we show that...

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Bibliographic Details
Main Authors: Tamara Utermark, Simone J.A. Schubert, C. Oliver Hanemann
Format: Article
Language:English
Published: Elsevier 2005-06-01
Series:Neurobiology of Disease
Subjects:
Tumor suppressor merlin
Intermediate filament
Perinuclear collapse
Rac activation
Tyrosine phosphorylation
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996104002852

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http://www.sciencedirect.com/science/article/pii/S0969996104002852

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