Immunological hotspots analyzed by docking simulations: evidence for a general mechanism in pemphigus vulgaris pathology and transformation
<p>Abstract</p> <p>Background</p> <p>Pemphigus vulgaris (PV) is an acquired autoimmune blistering disorder in which greater than 80% of active patients produce autoantibodies to the desmosomal protein desmogelin 3 (Dsg3). As the disease progresses, 40–50% of patients ma...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2008-06-01
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| Series: | BMC Immunology |
| Online Access: | http://www.biomedcentral.com/1471-2172/9/30 |