MicroRNA-29b-3p Promotes Human Retinal Microvascular Endothelial Cell Apoptosis via Blocking SIRT1 in Diabetic Retinopathy

MicroRNA-29b-3p Promotes Human Retinal Microvascular Endothelial Cell Apoptosis via Blocking SIRT1 in Diabetic Retinopathy

BackgroundDiabetic retinopathy (DR) is a main complication of diabetes mellitus (DM). Recent studies have implicated microRNAs in human retinal microvascular endothelial cell (HRMEC) dysfunction. In this study, we aim to investigate the apoptotic promotion of miR-29b-3p by blocking SIRT1 in HRMEC fo...

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Bibliographic Details
Main Authors: Yong Zeng, Zekai Cui, Jian Liu, Jiansu Chen, Shibo Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Physiology
Subjects:
diabetic retinopathy
miR-29b-3p
SIRT1
human retinal microvascular endothelial cell
apoptosis
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01621/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.01621/full

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