CYFIP1 is directly controlled by NOTCH1 and down-regulated in cutaneous squamous cell carcinoma.

Squamous cell carcinoma of the skin (SCC) represents one of the most common cancers in the general population and is associated with a substantial risk of metastasis. Previous work uncovered the functional role of CYFIP1 in epithelial tumors as an invasion inhibitor. It was down-regulated in some ca...

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Bibliographic Details
Main Authors: Piotr J Dziunycz, Johannes Neu, Karine Lefort, Nadia Djerbi, Sandra N Freiberger, Guergana Iotzova-Weiss, Lars E French, Gian-Paolo Dotto, Günther F Hofbauer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5391925?pdf=render