Combinatorial engineering of dextransucrase specificity.

We used combinatorial engineering to investigate the relationships between structure and linkage specificity of the dextransucrase DSR-S from Leuconostoc mesenteroides NRRL B-512F, and to generate variants with altered specificity. Sequence and structural analysis of glycoside-hydrolase family 70 en...

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Bibliographic Details
Main Authors: Romain Irague, Laurence Tarquis, Isabelle André, Claire Moulis, Sandrine Morel, Pierre Monsan, Gabrielle Potocki-Véronèse, Magali Remaud-Siméon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3799614?pdf=render