Calcium and IP3 dynamics in cardiac myocytes: Experimental and computational perspectives and approaches

Calcium plays a crucial role in excitation-contraction coupling (ECC), but it is also a pivotal second messenger activating Ca2+-dependent transcription factors in a process termed excitation-transcription coupling (ETC). Evidence accumulated over the past decade indicates a pivotal role of inositol...

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Bibliographic Details
Main Authors: Felix eHohendanner, Andrew D McCulloch, Lothar A Blatter, Anushka P Michailova
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Pharmacology
Subjects:
IP3
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00035/full