Presynaptic plasticity as a hallmark of rat stress susceptibility and antidepressant response.

Two main questions are important for understanding and treating affective disorders: why are certain individuals susceptible or resilient to stress, and what are the features of treatment response and resistance? To address these questions, we used a chronic mild stress (CMS) rat model of depression...

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Bibliographic Details
Main Authors: Jose Luis Nieto-Gonzalez, Mai Marie Holm, Irina Vardya, Trine Christensen, Ove Wiborg, Kimmo Jensen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4350919?pdf=render