Virologic suppression in response to antiretroviral therapy despite extensive resistance within HIV-1 reverse transcriptase after the first virologic failure

Virologic suppression in response to antiretroviral therapy despite extensive resistance within HIV-1 reverse transcriptase after the first virologic failure

Abstract Background Incomplete virologic suppression results in mutations associated with resistance and is a major obstacle to disease control. We analyzed the genotypic profiles of HIV-1 patients at the time of the first virologic failure and the response to a salvage regimen after 48 weeks. Metho...

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Bibliographic Details
Main Authors: Marta Iglis Oliveira, Valter Romão de Souza Junior, Claudia Fernanda de Lacerda Vidal, Paulo Sérgio Ramos de Araújo
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Infectious Diseases
Subjects:
HIV-1 drug resistance
Genetic diversity
Subtypes
Antiretroviral therapy
Online Access:http://link.springer.com/article/10.1186/s12879-018-3400-6

Internet

http://link.springer.com/article/10.1186/s12879-018-3400-6

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