BMI1 in the heart: Novel functions beyond tumorigenesis

The BMI1 protein, a member of the PRC1 family, is a well recognised transcriptional suppressor and has the capability of maintaining the self-renewal and proliferation of tissue-specific stem cells. Numerous studies have established that BMI1 is highly expressed in a variety of malignant cancers and...

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Bibliographic Details
Main Authors: Dan Yang, Han-Qing Liu, Zheng Yang, Di Fan, Qi-Zhu Tang
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420305697