Pulmonary Arterial Hypertension Affects the Rat Gut Microbiome

Pulmonary Arterial Hypertension Affects the Rat Gut Microbiome

Abstract We have analysed whether pulmonary arterial hypertension (PAH) alters the rat faecal microbiota. Wistar rats were injected with the VEGF receptor antagonist SU5416 (20 mg/kg s.c.) and followed for 2 weeks kept in hypoxia (10% O2, PAH) or injected with vehicle and kept in normoxia (controls)...

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Main Authors: María Callejo, Gema Mondejar-Parreño, Bianca Barreira, José L. Izquierdo-Garcia, Daniel Morales-Cano, Sergio Esquivel-Ruiz, Laura Moreno, Ángel Cogolludo, Juan Duarte, Francisco Perez-Vizcaino
Format: Article
Language:English
Published: Nature Publishing Group 2018-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-27682-w

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https://doi.org/10.1038/s41598-018-27682-w

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