Single molecule analysis of replicated DNA reveals the usage of multiple KSHV genome regions for latent replication.

Single molecule analysis of replicated DNA reveals the usage of multiple KSHV genome regions for latent replication.

Kaposi's sarcoma associated herpesvirus (KSHV), an etiologic agent of Kaposi's sarcoma, Body Cavity Based Lymphoma and Multicentric Castleman's Disease, establishes lifelong latency in infected cells. The KSHV genome tethers to the host chromosome with the help of a latency associated...

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Bibliographic Details
Main Authors: Subhash C Verma, Jie Lu, Qiliang Cai, Settapong Kosiyatrakul, Maria E McDowell, Carl L Schildkraut, Erle S Robertson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3207954?pdf=render

Internet

http://europepmc.org/articles/PMC3207954?pdf=render

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