Development and preclinical evaluation of novel fluorinated ammonium salts for PET myocardial perfusion imaging

Abstract We previously presented the radiolabeled ammonium salt [11C]-dimethyl diphenylammonium trifluoromethanesulfonate ([11C]DMDPA) as a potential novel PET-MPI agent. The current study aimed to increase the clinical applicability of PET-MPI by designing and synthesizing fluorinated ammonium salt...

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Bibliographic Details
Main Authors: Ofer Shamni, Hilbert Grievink, Netanel Kolevzon, Seweryn Krajewski, Lukasz Steczek, Ella Meltzer, Shimon Yitshak, Eyal Mishani, Galith Abourbeh
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-99212-0