Patient-specific organotypic blood vessels as an in vitro model for anti-angiogenic drug response testing in renal cell carcinomaResearch in context

Background: Anti-angiogenic treatment failure is often attributed to drug resistance, unsuccessful drug delivery, and tumor heterogeneity. Recent studies have speculated that anti-angiogenic treatments may fail due to characteristics inherent to tumor-associated blood vessels. Tumor-associated blood...

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Bibliographic Details
Main Authors: José A. Jiménez-Torres, María Virumbrales-Muñoz, Kyung E. Sung, Moon Hee Lee, E. Jason Abel, David J. Beebe
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419301665