Structural rearrangements of the histone octamer translocate DNA

Nucleosomes are dynamic and can move along DNA in an uncatalyzed manner but little is known about the mechanisms of histone octamer translocation. Here the authors present cryo-EM structures of nucleosomes in differently organized histone octamer and DNA states and show how histone octamers transloc...

Full description

Bibliographic Details
Main Authors: Silvija Bilokapic, Mike Strauss, Mario Halic
Format: Article
Language:English
Published: Nature Publishing Group 2018-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03677-z