Clinical features and genotype-phenotype correlation analysis in patients with ATL1 mutations: A literature reanalysis

Clinical features and genotype-phenotype correlation analysis in patients with ATL1 mutations: A literature reanalysis

Abstract Background The hereditary spastic paraplegias (HSPs) are a group of clinically and genetically heterogeneous disorders. Approximately 10% of the autosomal dominant (AD) HSPs (ADHSPs) have the spastic paraplegia 3A (SPG3A) genotype which is caused by ATL1 gene mutations. Currently there are...

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Bibliographic Details
Main Authors: Guo-hua Zhao, Xiao-min Liu
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Translational Neurodegeneration
Subjects:
Hereditary spastic paraplegia
SPG3A
Age at onset
ATL1
Mutation
Genotype-phenotype correlation
Online Access:http://link.springer.com/article/10.1186/s40035-017-0079-3

Internet

http://link.springer.com/article/10.1186/s40035-017-0079-3

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