Macrophage pro-inflammatory response to Francisella novicida infection is regulated by SHIP.

Francisella tularensis, a Gram-negative facultative intracellular pathogen infecting principally macrophages and monocytes, is the etiological agent of tularemia. Macrophage responses to F. tularensis infection include the production of pro-inflammatory cytokines such as interleukin (IL)-12, which i...

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Main Authors: Kishore V L Parsa, Latha P Ganesan, Murugesan V S Rajaram, Mikhail A Gavrilin, Ashwin Balagopal, Nrusingh P Mohapatra, Mark D Wewers, Larry S Schlesinger, John S Gunn, Susheela Tridandapani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC1513262?pdf=render