New Paracyclophanylthiazoles with Anti-Leukemia Activity: Design, Synthesis, Molecular Docking, and Mechanistic Studies

New Paracyclophanylthiazoles with Anti-Leukemia Activity: Design, Synthesis, Molecular Docking, and Mechanistic Studies

A new series of methyl 2-(2-(4′-[2.2]paracyclophanyl)-hydrazinylidene)-3-substituted-4-oxothiazolidin-5-ylidene)acetates <b>3a</b>–<b>f</b> were synthesized from the reaction of paracyclophanyl-acylthiosemicarbazides <b>2a</b>–<b>f</b> with dimethyl ac...

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Bibliographic Details
Main Authors: Ashraf A Aly, Stefan Bräse, Alaa A. Hassan, Nasr K. Mohamed, Lamiaa E. Abd El-Haleem, Martin Nieger, Nesrin M. Morsy, Elshimaa M. N. Abdelhafez
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Molecules
Subjects:
paracyclophanes
NMR
X-ray
NCI-60
cancer cell lines
mechanism
Online Access:https://www.mdpi.com/1420-3049/25/13/3089

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https://www.mdpi.com/1420-3049/25/13/3089

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