Profound alteration in cutaneous primary afferent activity produced by inflammatory mediators

Inflammatory pain is thought to arise from increased transmission from nociceptors and recruitment of 'silent' afferents. To evaluate inflammation-induced changes, mice expressing GCaMP3 in cutaneous sensory neurons were generated and neuronal responses to mechanical stimulation in vivo be...

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Bibliographic Details
Main Authors: Kristen M Smith-Edwards, Jennifer J DeBerry, Jami L Saloman, Brian M Davis, C Jeffery Woodbury
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-11-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/20527