Profound alteration in cutaneous primary afferent activity produced by inflammatory mediators
Inflammatory pain is thought to arise from increased transmission from nociceptors and recruitment of 'silent' afferents. To evaluate inflammation-induced changes, mice expressing GCaMP3 in cutaneous sensory neurons were generated and neuronal responses to mechanical stimulation in vivo be...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2016-11-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/20527 |