Prevalence of <it>von Hippel-Lindau </it>gene mutations in sporadic renal cell carcinoma: results from the Netherlands cohort study

Prevalence of <it>von Hippel-Lindau </it>gene mutations in sporadic renal cell carcinoma: results from the Netherlands cohort study

<p>Abstract</p> <p>Background</p> <p>Biallelic <it>von Hippel-Lindau </it>(<it>VHL</it>) gene defects, a rate-limiting event in the carcinogenesis, occur in approximately 75% of sporadic clear-cell Renal Cell Carcinoma (RCC). We studied the <i...

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Main Authors: Schalken Jack A, Gorissen Hanneke JM, Schouten Leo J, Hulsbergen-van de Kaa Christina A, van Dijk Boukje AC, van Houwelingen Kjeld P, van den Brandt Piet A, Oosterwijk Egbert
Format: Article
Language:English
Published: BMC 2005-06-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/5/57

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http://www.biomedcentral.com/1471-2407/5/57

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