Effects of methacholine infusion on desflurane pharmacokinetics in piglets

Effects of methacholine infusion on desflurane pharmacokinetics in piglets

The data of a corresponding animal experiment demonstrates that nebulized methacholine (MCh) induced severe bronchoconstriction and significant inhomogeneous ventilation and pulmonary perfusion (V̇A/Q̇) distribution in pigs, which is similar to findings in human asthma. The inhalation of MCh induced...

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Bibliographic Details
Main Authors: Alf Kozian, Moritz Kretzschmar, James E. Baumgardner, Jens Schreiber, Göran Hedenstierna, Anders Larsson, Thomas Hachenberg, Thomas Schilling
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Data in Brief
Subjects:
Animal model
Alveolar ventilation
Desflurane
Arterial blood gas concentration
Bronchoconstriction
Ventilation-/perfusion-mismatch
Methacholine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340915002966

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http://www.sciencedirect.com/science/article/pii/S2352340915002966

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