Nanotopographical Coatings Induce an Early Phenotype-Specific Response of Primary Material-Resident M1 and M2 Macrophages

Nanotopographical Coatings Induce an Early Phenotype-Specific Response of Primary Material-Resident M1 and M2 Macrophages

Implants elicit an immunological response after implantation that results in the worst case in a complete implant rejection. This biomaterial-induced inflammation is modulated by macrophages and can be influenced by nanotopographical surface structures such as titania nanotubes or fractal titanium n...

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Bibliographic Details
Main Authors: Tobias Schmitz, Maren Jannasch, Tobias Weigel, Claus Moseke, Uwe Gbureck, Jürgen Groll, Heike Walles, Jan Hansmann
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Materials
Subjects:
nanotopographical surfaces
combination of physical vapor deposition and electrochemical etching
defined humanized test system
inflammatory response
Online Access:https://www.mdpi.com/1996-1944/13/5/1142

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https://www.mdpi.com/1996-1944/13/5/1142

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