Ehrlichia chaffeensis and Its Invasin EtpE Block Reactive Oxygen Species Generation by Macrophages in a DNase X-Dependent Manner

The obligatory intracellular pathogen Ehrlichia chaffeensis lacks most genes that confer resistance to oxidative stress but can block reactive oxygen species (ROS) generation by host monocytes-macrophages. Bacterial and host molecules responsible for this inhibition have not been identified. To infe...

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Bibliographic Details
Main Authors: Omid Teymournejad, Mingqun Lin, Yasuko Rikihisa, Howard A. Shuman
Format: Article
Language:English
Published: American Society for Microbiology 2017-11-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/6/e01551-17