Increase of reactive oxygen species contributes to growth inhibition by fluconazole in Cryptococcus neoformans

Increase of reactive oxygen species contributes to growth inhibition by fluconazole in Cryptococcus neoformans

Abstract Background Cryptococcus neoformans, a basidiomycetous yeast, is a fungal pathogen that can colonize the lungs of humans causing pneumonia and fungal meningitis in severely immunocompromised individuals. Recent studies have implied that the antifungal drug fluconazole (FLC) can induce oxidat...

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Bibliographic Details
Main Authors: Nadir Hani Dbouk, Madison Bailey Covington, Kenny Nguyen, Srikripa Chandrasekaran
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Microbiology
Subjects:
Antifungal treatment
Antioxidants
ROS
Metallothionein
Online Access:http://link.springer.com/article/10.1186/s12866-019-1606-4

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http://link.springer.com/article/10.1186/s12866-019-1606-4

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