The Toll-like receptor ligand, CpG oligodeoxynucleotides, regulate proliferation and osteogenic differentiation of osteoblast

The Toll-like receptor ligand, CpG oligodeoxynucleotides, regulate proliferation and osteogenic differentiation of osteoblast

Abstract Background This study aimed to investigate the regulation of CpG oligodeoxynucleotides (ODNs) on proliferation and osteogenic differentiation of MC3T3 cells. Methods The laser co-focusing and flow cytometry assay were employed to detect cell uptake of CpG ODN 2006. Twelve ODNs were sythesiz...

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Bibliographic Details
Main Authors: Wenwen Yu, Yi Zheng, Hongyan Li, Hongbing Lin, Zhen Chen, Yue Tian, Huishan Chen, Peipei Zhang, Xiaowei Xu, Yuqin Shen
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Periodontitis
CpG ODN
Osteoblast
Proliferation
Differentiation
Online Access:http://link.springer.com/article/10.1186/s13018-020-01844-x

Internet

http://link.springer.com/article/10.1186/s13018-020-01844-x

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