Human ESCs predisposition to karyotypic instability: Is a matter of culture adaptation or differential vulnerability among hESC lines due to inherent properties?

<p>Abstract</p> <p>Background</p> <p>The use of human embryonic stem cells (hESCs) in research is increasing and hESCs hold the promise for many biological, clinical and toxicological studies. Human ESCs are expected to be chromosomally stable since karyotypic changes r...

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Bibliographic Details
Main Authors: Bueno Clara, de la Cueva Teresa, Sanchez Laura, Ligero Gertru, Montes Rosa, Catalina Puri, Leone Paola E, Menendez Pablo
Format: Article
Language:English
Published: BMC 2008-10-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/7/1/76