Structure-Activity Relationship (SAR) and in vitro Predictions of Mutagenic and Carcinogenic Activities of Ixodicidal Ethyl-Carbamates

Ethyl-4-bromophenyl-carbamate (LQM 919) and Ethyl-4-chlorophenyl-carbamate (LQM 996) are compounds that inhibit egg-laying and hatching of tick larvae that are resistant to conventional ixodicides. The structure-activity relationship (SAR) to get the endpoint predictions of mutagenicity and carcinog...

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Main Authors: María G. Prado-Ochoa, Maribel Strassburger-Madrigal, Rafael Camacho-Carranza, Jesús J. Espinosa-Aguirre, Ana M. Velázquez-Sánchez, Victor H. Vázquez-Valadez, Enrique Angeles, Fernando Alba-Hurtado, Marco A. Muñoz-Guzmán
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2020/2981681