The C-terminal domain of the MutL homolog from Neisseria gonorrhoeae forms an inverted homodimer.

The C-terminal domain of the MutL homolog from Neisseria gonorrhoeae forms an inverted homodimer.

The mismatch repair (MMR) pathway serves to maintain the integrity of the genome by removing mispaired bases from the newly synthesized strand. In E. coli, MutS, MutL and MutH coordinate to discriminate the daughter strand through a mechanism involving lack of methylation on the new strand. This fac...

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Bibliographic Details
Main Authors: Sivakumar Namadurai, Deepti Jain, Dhananjay S Kulkarni, Chaitanya R Tabib, Peter Friedhoff, Desirazu N Rao, Deepak T Nair
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2965676?pdf=render

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http://europepmc.org/articles/PMC2965676?pdf=render

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