Mycobacterium tuberculosis multidrug resistant strain M induces an altered activation of cytotoxic CD8+ T cells.

Mycobacterium tuberculosis multidrug resistant strain M induces an altered activation of cytotoxic CD8+ T cells.

In human tuberculosis (TB), CD8+ T cells contribute to host defense by the release of Th1 cytokines and the direct killing of Mycobacterium tuberculosis (Mtb)-infected macrophages via granule exocytosis pathway or the engagement of receptors on target cells. Previously we demonstrated that strain M,...

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Bibliographic Details
Main Authors: Laura Geffner, Juan Ignacio Basile, Noemí Yokobori, Denise Kviatcovsky, Carmen Sabio y García, Viviana Ritacco, Beatriz López, María del Carmen Sasiain, Silvia de la Barrera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4024032?pdf=render

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http://europepmc.org/articles/PMC4024032?pdf=render

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