Novel and ultra-rare damaging variants in neuropeptide signaling are associated with disordered eating behaviors.

OBJECTIVE:Eating disorders develop through a combination of genetic vulnerability and environmental stress, however the genetic basis of this risk is unknown. METHODS:To understand the genetic basis of this risk, we performed whole exome sequencing on 93 unrelated individuals with eating disorders (...

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Bibliographic Details
Main Authors: Michael Lutter, Ethan Bahl, Claire Hannah, Dabney Hofammann, Summer Acevedo, Huxing Cui, Carrie J McAdams, Jacob J Michaelson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5573281?pdf=render