Discovery of Anti-Hypertensive Oligopeptides from Adlay Based on In Silico Proteolysis and Virtual Screening

Discovery of Anti-Hypertensive Oligopeptides from Adlay Based on In Silico Proteolysis and Virtual Screening

Adlay (Coix larchryma-jobi L.) was the commonly used Traditional Chinese Medicine (TCM) with high content of seed storage protein. The hydrolyzed bioactive oligopeptides of adlay have been proven to be anti-hypertensive effective components. However, the structures and anti-hypertensive mechanism of...

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Bibliographic Details
Main Authors: Liansheng Qiao, Bin Li, Yankun Chen, Lingling Li, Xi Chen, Lingzhi Wang, Fang Lu, Ganggang Luo, Gongyu Li, Yanling Zhang
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Series:International Journal of Molecular Sciences
Subjects:
adlay
hypertension
oligopeptides
angiotensin-I converting enzyme (ACE)
in silico proteolysis
molecular dynamics (MD)
Online Access:http://www.mdpi.com/1422-0067/17/12/2099

Internet

http://www.mdpi.com/1422-0067/17/12/2099

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