Modulation of Pro-Oxidant and Pro-Inflammatory Activities of M1 Macrophages by the Natural Dipeptide Carnosine

Modulation of Pro-Oxidant and Pro-Inflammatory Activities of M1 Macrophages by the Natural Dipeptide Carnosine

Carnosine is a natural endogenous dipeptide widely distributed in mammalian tissues, existing at particularly high concentrations in the muscles and brain and possesses well-characterized antioxidant and anti-inflammatory activities. In an in vitro model of macrophage activation, induced by lipopoly...

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Bibliographic Details
Main Authors: Claudia G. Fresta, Annamaria Fidilio, Giacomo Lazzarino, Nicolò Musso, Margherita Grasso, Sara Merlo, Angela M. Amorini, Claudio Bucolo, Barbara Tavazzi, Giuseppe Lazzarino, Susan M. Lunte, Filippo Caraci, Giuseppe Caruso
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:International Journal of Molecular Sciences
Subjects:
carnosine
m1 macrophages
nitric oxide
oxidative stress
inflammation
antioxidants
energy metabolism
Online Access:https://www.mdpi.com/1422-0067/21/3/776

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https://www.mdpi.com/1422-0067/21/3/776

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