Switching off angiogenic signalling: creating channelled constructs for adequate oxygen delivery in tissue engineered constructs
A major question in biomimetic tissue engineering is how much of the structure/function of native vasculature needs to be reproduced for effective tissue perfusion. O2 supplied to cells in 3D scaffolds in vitro is initially dependent upon diffusion through the scaffold and cell consumption. Low O2 (...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
AO Research Institute Davos
2010-10-01
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| Series: | European Cells & Materials |
| Subjects: | |
| Online Access: | http://www.ecmjournal.org/journal/papers/vol020/pdf/v020a22.pdf |