SFRP5 Enhances Wnt5a Induced-Inflammation in Rheumatoid Arthritis Fibroblast-Like Synoviocytes

SFRP5 Enhances Wnt5a Induced-Inflammation in Rheumatoid Arthritis Fibroblast-Like Synoviocytes

BackgroundTissue derived fibroblast-like synoviocytes (td-FLS) are key actors in pannus formation and contribute to joint destruction and inflammation during rheumatoid arthritis (RA). Several members of the Wnt family, including Wnt5a, may contribute to RA td-FLS activation and can potentially serv...

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Bibliographic Details
Main Authors: Dorra Elhaj Mahmoud, Wajih Kaabachi, Nadia Sassi, Amel Mokhtar, Myriam Moalla, Lobna Ben Ammar, Samia Jemmali, Sonia Rekik, Lamjed Tarhouni, Maryam Kallel-Sellami, Elhem Cheour, Lilia Laadhar
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
rheumatoid arthritis
Wnt pathway
FLS
fibrocytes
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.663683/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.663683/full

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