Integrative genomic analysis identifies that SERPINA6-rs1998056 regulated by FOXA/ERα is associated with female hepatocellular carcinoma.

Integrative genomic analysis identifies that SERPINA6-rs1998056 regulated by FOXA/ERα is associated with female hepatocellular carcinoma.

The human forkhead box A1 (FOXA1) and A2 (FOXA2) transcription factors have been found to control estrogen and androgen signaling through co-regulating target genes with sex hormone receptors. Here we used an integrative strategy to examine the hypothesis that genetic variants at FOXA1/2 binding ele...

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Bibliographic Details
Main Authors: Na Shen, Jing Gong, Ying Wang, Jing Tian, Jiaming Qian, Li Zou, Wei Chen, Beibei Zhu, Xinghua Lu, Rong Zhong, Anyuan Guo, Li Wang, Xiaoping Miao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4157870?pdf=render

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http://europepmc.org/articles/PMC4157870?pdf=render

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