Analysis of pleiotropic transcriptional profiles: a case study of DNA gyrase inhibition.

Genetic and environmental perturbations often result in complex transcriptional responses involving multiple genes and regulons. In order to understand the nature of a response, one has to account for the contribution of the downstream effects to the formation of a response. Such analysis can be car...

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Bibliographic Details
Main Authors: Kyeong Soo Jeong, Yang Xie, Hiroshi Hiasa, Arkady B Khodursky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1584274?pdf=render