Association Between Leukocyte Mitochondrial DNA Copy Number and Non-alcoholic Fatty Liver Disease in a Chinese Population Is Mediated by 8-Oxo-2′-Deoxyguanosine

Association Between Leukocyte Mitochondrial DNA Copy Number and Non-alcoholic Fatty Liver Disease in a Chinese Population Is Mediated by 8-Oxo-2′-Deoxyguanosine

Background: Alterations in mitochondrial DNA are potentially associated with oxidative stress and may be involved in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). However, the association between mitochondrial DNA copy number (mtDNAcn) and NAFLD was not consistent. In addition, the...

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Bibliographic Details
Main Authors: Chifa Ma, Yiwen Liu, Shuli He, Jingbo Zeng, Pingping Li, Chunxiao Ma, Fan Ping, Huabing Zhang, Lingling Xu, Wei Li, Yuxiu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Medicine
Subjects:
inflammation markers
leukocyte mitochondrial DNA copy number
non-alcoholic fatty liver disease
oxidative stress
8-oxo-2′-deoxyguanosine
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00536/full

Internet

https://www.frontiersin.org/article/10.3389/fmed.2020.00536/full

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