Novel strains of mice deficient for the vesicular acetylcholine transporter: insights on transcriptional regulation and control of locomotor behavior.

Novel strains of mice deficient for the vesicular acetylcholine transporter: insights on transcriptional regulation and control of locomotor behavior.

Defining the contribution of acetylcholine to specific behaviors has been challenging, mainly because of the difficulty in generating suitable animal models of cholinergic dysfunction. We have recently shown that, by targeting the vesicular acetylcholine transporter (VAChT) gene, it is possible to g...

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Bibliographic Details
Main Authors: Cristina Martins-Silva, Xavier De Jaeger, Monica S Guzman, Ricardo D F Lima, Magda S Santos, Christopher Kushmerick, Marcus V Gomez, Marc G Caron, Marco A M Prado, Vania F Prado
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3053374?pdf=render

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http://europepmc.org/articles/PMC3053374?pdf=render

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